Plasmodium falciparum is one of the leading causes of global mortality. While the parasitic disease has been understood for a century, there has been limited success in its control. Modern efforts focus on improved chemotherapy as well as mosquito control programs. The limited budget of the afflicted countries demands efficient allocation of resources, which will ensure radical cure of the infected and protection of the healthy. Mathematical models of disease dynamics at the individual and global level may serve as a valuable tool. We discuss a few models and potential methods of linking them together, and raise the public health implications.
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